Pure nongestational choriocarcinoma of the ovary: a case report
نویسندگان
چکیده
Pure ovarian choriocarcinoma can be gestational or nongestational in origin. Nongestational choriocarcinoma of the ovary is extremely rare, and its diagnosis is very difficult during the reproductive years. We present a case of a 33-year-old woman diagnosed with pure nongestational ovarian choriocarcinoma. Following surgery, multiple courses of a chemotherapy regimen of etoposide, methotrexate, and actinomycin-D (EMA) were effective.
منابع مشابه
Ovary: Choriocarcinoma
Note Choriocarcinoma of the ovary is a highly malignant ovarian tumor which is characterized pathologically by the presence of trophoblastic malignant cells, and biochemically by the production of the pregnancy hormone human chorionic gonadotrophin (hCG) in the absence of an ongoing pregnancy. Choriocarcinoma tends to be invasive and to metastasize early and widely through both the venous and l...
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Choriocarcinoma of the ovary is a rare and highly malignant germ cell tumor. There are three ways in which an ovarian choriocarcinoma can arise: as a primary gestational choriocarcinoma that results from an ectopic ovarian pregnancy, as a metastatic choriocarcinoma that arises from a gestational choriocarcinoma, and as a germ cell tumor with differentiation into trophoblastic structures. Ovaria...
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Clinical diagnosis of choriocarcinoma may be difficult in post-menopause or children and ectopic origin. According to its histologic origin, it is classified as gestational or nongestational choriocarcinoma. Gestational choriocarcinoma its origin derived from placental trophoblast and nongestational choriocarcinoma-derived from a germ cell. However, DNA and genetic analysis can be used to defin...
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عنوان ژورنال:
دوره 11 شماره
صفحات -
تاریخ انتشار 2013